In a groundbreaking advancement, a patient with amyotrophic lateral sclerosis (ALS) has successfully operated an iPad solely through thought, utilizing Apple’s Brain-Computer Interface Human Interface Device (BCI HID) protocol in conjunction with Synchron’s innovative technology.
Apple’s BCI HID protocol, introduced in May 2025, provides a standardized set of controls accessible via an API, enabling developers to integrate brain-computer interface capabilities into their applications. This protocol was first demonstrated when Synchron showcased a patient using the Apple Vision Pro through thought control.
Recently, Synchron has unveiled a demonstration where the same patient, Mark Jackson, who has ALS and has lost the use of his hands, operates an iPad entirely through thought. This marks a significant milestone in human-computer interaction.
Dr. Tom Oxley, CEO and Founder of Synchron, stated, This is the first time the world has seen native, thought-driven control of an Apple device in action. It is a technical breakthrough and a glimpse into the future of human-computer interaction, where cognitive input becomes a mainstream mode of control.
While Synchron had previously demonstrated iPad control in 2022, the earlier system allowed patients to send single-word text messages. The current demonstration showcases complete control of the device, including launching apps and full usage.
Mark Jackson, the patient involved, expressed his experience: When I lost the use of my hands, I thought I had lost my independence. Now, with my iPad, I can message my loved ones, read the news, and stay connected with the world, just by thinking.
The system operates by implanting a device called a Stentrode into a vein on the brain’s motor cortex. This device detects motor intent and transmits the signals to an external device that connects to the iPad through Apple’s BCI HID protocol. The integration also utilizes Apple’s Switch Control accessibility feature, allowing users to navigate and control the iPad interface seamlessly.
This development offers a new avenue for individuals with paralysis or severe motor impairments to interact with technology, enhancing their independence and quality of life.
